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Hydrophilic microenvironment required for the channel-independent insertase function of YidC protein

The recently solved crystal structure of YidC protein suggests that it mediates membrane protein insertion by means of an intramembrane cavity rather than a transmembrane (TM) pore. This concept of protein translocation prompted us to characterize the native, membrane-integrated state of YidC with r...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Proc Natl Acad Sci U S A
Prif Awduron: Shimokawa-Chiba, Naomi, Kumazaki, Kaoru, Tsukazaki, Tomoya, Nureki, Osamu, Ito, Koreaki, Chiba, Shinobu
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413333/
https://ncbi.nlm.nih.gov/pubmed/25855636
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423817112
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