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Towards mapping the 3D genome through high speed single-molecule tracking of functional transcription factors in single living cells
How genomic DNA is organized in the nucleus is a long-standing question. We describe a single-molecule bioimaging method utilizing super-localization precision coupled to fully quantitative image analysis tools, towards determining snapshots of parts of the 3D genome architecture of model eukaryote...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | Methods |
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| Κύριοι συγγραφείς: | , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
Academic Press
2020
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6971689/ https://ncbi.nlm.nih.gov/pubmed/31252059 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymeth.2019.06.021 |
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