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Transcription factor clusters regulate genes in eukaryotic cells

Transcription is regulated through binding factors to gene promoters to activate or repress expression, however, the mechanisms by which factors find targets remain unclear. Using single-molecule fluorescence microscopy, we determined in vivo stoichiometry and spatiotemporal dynamics of a GFP tagged...

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Bibliografski detalji
Izdano u:eLife
Glavni autori: Wollman, Adam JM, Shashkova, Sviatlana, Hedlund, Erik G, Friemann, Rosmarie, Hohmann, Stefan, Leake, Mark C
Format: Artigo
Jezik:Inglês
Izdano: eLife Sciences Publications, Ltd 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5602325/
https://ncbi.nlm.nih.gov/pubmed/28841133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.27451
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