3D ultrastructural analysis of α‐granule, dense granule, mitochondria, and canalicular system arrangement in resting human platelets

BACKGROUND: State‐of‐the‐art 3‐dimensional (3D) electron microscopy approaches provide a new standard for the visualization of human platelet ultrastructure. Application of these approaches to platelets rapidly fixed prior to purification to minimize activation should provide new insights into resti...

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Pubblicato in:Res Pract Thromb Haemost
Autori principali: Pokrovskaya, Irina D., Yadav, Shilpi, Rao, Amith, McBride, Emma, Kamykowski, Jeffrey A., Zhang, Guofeng, Aronova, Maria A., Leapman, Richard D., Storrie, Brian
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2019
Soggetti:
Original Articles: Hemostasis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971324/
https://ncbi.nlm.nih.gov/pubmed/31989087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/rth2.12260
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