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STEM Tomography Reveals that the Canalicular System and α-Granules Remain Separate Compartments During Early Secretion Stages in Blood Platelets

BACKGROUND: Platelets survey the vasculature for damage and, in response, activate and release a wide range of proteins from their α-granules. Alpha-granules may be biochemically and structurally heterogeneous; however, other studies suggest that they may be more homogeneous with the observed variat...

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Bibliografske podrobnosti
izdano v:J Thromb Haemost
Main Authors: Pokrovskaya, Irina D., Aronova, Maria A., Kamykowski, Jeffrey A., Prince, Andrew A., Hoyne, Jake D., Calco, Gina N., Kuo, Bryan C., He, Qianping, Leapman, Richard D., Storrie, Brian
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4829117/
https://ncbi.nlm.nih.gov/pubmed/26663480
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.13225
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