Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification

The extracellular matrix (ECM) of tissues is susceptible to modification by inflammation-associated oxidants. Considerable data support a role for hypochlorous acid (HOCl), generated by the leukocyte-derived heme-protein myeloperoxidase (MPO) in these changes. HOCl can modify isolated ECM proteins a...

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Vydáno v:Sci Rep
Hlavní autoři: Cai, Huan, Chuang, Christine Y., Hawkins, Clare L., Davies, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971288/
https://ncbi.nlm.nih.gov/pubmed/31959784
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57299-6
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