Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase

Basement membranes are specialized extracellular matrices that underlie arterial wall endothelial cells, with laminin being a key structural and biologically-active component. Hypochlorous acid (HOCl), a potent oxidizing and chlorinating agent, is formed in vivo at sites of inflammation via the enzy...

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Pubblicato in:Redox Biol
Autori principali: Nybo, Tina, Dieterich, Simon, Gamon, Luke F., Chuang, Christine Y., Hammer, Astrid, Hoefler, Gerald, Malle, Ernst, Rogowska-Wrzesinska, Adelina, Davies, Michael J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260226/
https://ncbi.nlm.nih.gov/pubmed/30476874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.10.022
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