Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase

Basement membranes are specialized extracellular matrices that underlie arterial wall endothelial cells, with laminin being a key structural and biologically-active component. Hypochlorous acid (HOCl), a potent oxidizing and chlorinating agent, is formed in vivo at sites of inflammation via the enzy...

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Vydáno v:Redox Biol
Hlavní autoři: Nybo, Tina, Dieterich, Simon, Gamon, Luke F., Chuang, Christine Y., Hammer, Astrid, Hoefler, Gerald, Malle, Ernst, Rogowska-Wrzesinska, Adelina, Davies, Michael J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
Research Paper
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260226/
https://ncbi.nlm.nih.gov/pubmed/30476874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.10.022
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