Chlorination and oxidation of the extracellular matrix protein laminin and basement membrane extracts by hypochlorous acid and myeloperoxidase

Basement membranes are specialized extracellular matrices that underlie arterial wall endothelial cells, with laminin being a key structural and biologically-active component. Hypochlorous acid (HOCl), a potent oxidizing and chlorinating agent, is formed in vivo at sites of inflammation via the enzy...

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Détails bibliographiques
Publié dans:Redox Biol
Auteurs principaux: Nybo, Tina, Dieterich, Simon, Gamon, Luke F., Chuang, Christine Y., Hammer, Astrid, Hoefler, Gerald, Malle, Ernst, Rogowska-Wrzesinska, Adelina, Davies, Michael J.
Format: Artigo
Langue:Inglês
Publié: Elsevier 2018
Sujets:
Research Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6260226/
https://ncbi.nlm.nih.gov/pubmed/30476874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.10.022
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