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Binding of myeloperoxidase to the extracellular matrix of smooth muscle cells and subsequent matrix modification
The extracellular matrix (ECM) of tissues is susceptible to modification by inflammation-associated oxidants. Considerable data support a role for hypochlorous acid (HOCl), generated by the leukocyte-derived heme-protein myeloperoxidase (MPO) in these changes. HOCl can modify isolated ECM proteins a...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2020
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6971288/ https://ncbi.nlm.nih.gov/pubmed/31959784 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57299-6 |
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