Transmissible gastroenteritis virus targets Paneth cells to inhibit the self-renewal and differentiation of Lgr5 intestinal stem cells via Notch signaling

Infection with transmissible gastroenteritis virus (TGEV) has been associated with villous atrophy within 48 h, which seriously disrupts intestinal homeostasis. However, the underlying mechanisms remain elusive. In this study, we found that TGEV infection severely disrupted intestinal homeostasis vi...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Cell Death Dis
Главные авторы: Wu, Aimin, Yu, Bing, Zhang, Keying, Xu, Zhiwen, Wu, De, He, Jun, Luo, Junqiu, Luo, Yuheng, Yu, Jie, Zheng, Ping, Che, Lianqiang, Mao, Xiangbing, Huang, Zhiqing, Wang, Lan, Zhao, Jun, Chen, Daiwen
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2020
Предметы:
Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6971083/
https://ncbi.nlm.nih.gov/pubmed/31959773
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2233-6
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы