Pro-inflammatory macrophages coupled with glycolysis remodel adipose vasculature by producing platelet-derived growth factor-B in obesity

Adipose tissue macrophages (ATMs) play a central role in tissue remodeling and homeostasis. However, whether ATMs promote adipose angiogenesis in obesity remains unclear. We examined the impact of ATMs deletion on adipose angiogenesis and tissue expansion in the epididymal white adipose tissue (eWAT...

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Publicado en:Sci Rep
Autores principales: Onogi, Yasuhiro, Wada, Tsutomu, Okekawa, Akira, Matsuzawa, Takatoshi, Watanabe, Eri, Ikeda, Keisuke, Nakano, Minoru, Kitada, Munehiro, Koya, Daisuke, Tsuneki, Hiroshi, Sasaoka, Toshiyasu
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970998/
https://ncbi.nlm.nih.gov/pubmed/31959796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57368-w
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