Pro-inflammatory macrophages coupled with glycolysis remodel adipose vasculature by producing platelet-derived growth factor-B in obesity

Adipose tissue macrophages (ATMs) play a central role in tissue remodeling and homeostasis. However, whether ATMs promote adipose angiogenesis in obesity remains unclear. We examined the impact of ATMs deletion on adipose angiogenesis and tissue expansion in the epididymal white adipose tissue (eWAT...

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Xehetasun bibliografikoak
Argitaratua izan da:Sci Rep
Egile Nagusiak: Onogi, Yasuhiro, Wada, Tsutomu, Okekawa, Akira, Matsuzawa, Takatoshi, Watanabe, Eri, Ikeda, Keisuke, Nakano, Minoru, Kitada, Munehiro, Koya, Daisuke, Tsuneki, Hiroshi, Sasaoka, Toshiyasu
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Nature Publishing Group UK 2020
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970998/
https://ncbi.nlm.nih.gov/pubmed/31959796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57368-w
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