Loss of Endothelial Endoglin Promotes High-Output Heart Failure Through Peripheral Arteriovenous Shunting Driven by VEGF Signaling

RATIONALE: ENG (endoglin) is a coreceptor for BMP (bone morphogenetic protein) 9/10 and is strongly expressed in endothelial cells. Mutations in ENG lead to the inherited vascular disorder hereditary hemorrhagic telangiectasia characterized by local telangiectases and larger arteriovenous malformati...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Circ Res
Main Authors: Tual-Chalot, Simon, Garcia-Collado, Maria, Redgrave, Rachael E., Singh, Esha, Davison, Benjamin, Park, Catherine, Lin, Hua, Luli, Saimir, Jin, Yi, Wang, Yixin, Lawrie, Allan, Jakobsson, Lars, Arthur, Helen M.
Formato: Artigo
Idioma:Inglês
Publicado: Lippincott Williams & Wilkins 2020
Assuntos:
Original Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970547/
https://ncbi.nlm.nih.gov/pubmed/31805812
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.119.315974
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares