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Histone H3 Lysine 56 Acetylation Is Required for Formation of Normal Levels of Meiotic DNA Breaks in S. cerevisiae

Meiotic recombination is initiated by Spo11-catalyzed DNA double-strand breaks (DSBs) that are promoted by histone modifications and histone modifying enzymes. Herein we investigated the role of histone H3 lysine 56 acetylation (H3K56ac) located near the entry/exit points of the DNA in the globular...

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Publié dans:Front Cell Dev Biol
Auteurs principaux: Karányi, Zsolt, Hornyák, Lilla, Székvölgyi, Lóránt
Format: Artigo
Langue:Inglês
Publié: Frontiers Media S.A. 2020
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6970188/
https://ncbi.nlm.nih.gov/pubmed/31998719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fcell.2019.00364
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