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Initiation of Meiotic Homologous Recombination: Flexibility, Impact of Histone Modifications, and Chromatin Remodeling
Meiotic recombination is initiated by the formation of DNA double-strand breaks (DSBs) catalyzed by the evolutionary conserved Spo11 protein and accessory factors. DSBs are nonrandomly distributed along the chromosomes displaying a significant (∼400-fold) variation of frequencies, which ultimately e...
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| Publicado no: | Cold Spring Harb Perspect Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4448624/ https://ncbi.nlm.nih.gov/pubmed/25934010 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a016527 |
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