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Initiation of Meiotic Homologous Recombination: Flexibility, Impact of Histone Modifications, and Chromatin Remodeling

Meiotic recombination is initiated by the formation of DNA double-strand breaks (DSBs) catalyzed by the evolutionary conserved Spo11 protein and accessory factors. DSBs are nonrandomly distributed along the chromosomes displaying a significant (∼400-fold) variation of frequencies, which ultimately e...

詳細記述

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書誌詳細
出版年:Cold Spring Harb Perspect Biol
主要な著者: Székvölgyi, Lóránt, Ohta, Kunihiro, Nicolas, Alain
フォーマット: Artigo
言語:Inglês
出版事項: Cold Spring Harbor Laboratory Press 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4448624/
https://ncbi.nlm.nih.gov/pubmed/25934010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/cshperspect.a016527
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