Modulation of histone H3 lysine 56 acetylation as an antifungal therapeutic strategy

Candida albicans is a major fungal pathogen that causes serious systemic and mucosal infections in immunocompromised individuals. In yeast, histone H3 Lys56 acetylation (H3K56ac) is an abundant modification regulated by enzymes that have fungal-specific properties, making them appealing targets for...

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Bibliographic Details
Main Authors: Wurtele, Hugo, Tsao, Sarah, Lépine, Guylaine, Mullick, Alaka, Tremblay, Jessy, Drogaris, Paul, Lee, Eun-Hye, Thibault, Pierre, Verreault, Alain, Raymond, Martine
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4108442/
https://ncbi.nlm.nih.gov/pubmed/20601951
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2175
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