Histone Deacetylase Inhibitors Globally Enhance H3/H4 Tail Acetylation Without Affecting H3 Lysine 56 Acetylation

Histone deacetylase inhibitors (HDACi) represent a promising avenue for cancer therapy. We applied mass spectrometry (MS) to determine the impact of clinically relevant HDACi on global levels of histone acetylation. Intact histone profiling revealed that the HDACi SAHA and MS-275 globally increased...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Drogaris, Paul, Villeneuve, Valérie, Pomiès, Christelle, Lee, Eun-Hye, Bourdeau, Véronique, Bonneil, Éric, Ferbeyre, Gerardo, Verreault, Alain, Thibault, Pierre
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2012
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256565/
https://ncbi.nlm.nih.gov/pubmed/22355734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep00220
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller