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ISPD Overexpression Enhances Ribitol-Induced Glycosylation of α-Dystroglycan in Dystrophic FKRP Mutant Mice
Dystroglycanopathy, a subgroup of muscular dystrophies, is characterized by hypoglycosylation of α-dystroglycan (α-DG), which reduces its laminin-binding activity to extracellular matrix proteins, causing progressive loss of muscle integrity and function. Mutations in the fukutin-related protein (FK...
में बचाया:
| में प्रकाशित: | Mol Ther Methods Clin Dev |
|---|---|
| मुख्य लेखकों: | , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
American Society of Gene & Cell Therapy
2019
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6970132/ https://ncbi.nlm.nih.gov/pubmed/31988979 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.12.005 |
| टैग : |
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