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Distinct expression of functionally glycosylated alpha-dystroglycan in muscle and non-muscle tissues of FKRP mutant mice

The glycosylation of alpha-dystroglycan (α-DG) is crucial in maintaining muscle cell membrane integrity. Dystroglycanopathies are identified by the loss of this glycosylation leading to a breakdown of muscle cell membrane integrity and eventual degeneration. However, a small portion of fibers expres...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Blaeser, Anthony, Awano, Hiroyuki, Lu, Pei, Lu, Qi-Long
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5761899/
https://ncbi.nlm.nih.gov/pubmed/29320543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0191016
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