Activation of GLP-1 receptors attenuates oxycodone taking and seeking without compromising the antinociceptive effects of oxycodone in rats

Despite the effectiveness of current medications to treat opioid use disorder, there is still a high rate of relapse following detoxification. Thus, there is critical need for innovative studies aimed at identifying novel neurobiological mechanisms that could be targeted to treat opioid use disorder...

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Veröffentlicht in:Neuropsychopharmacology
Hauptverfasser: Zhang, Yafang, Kahng, Michelle W., Elkind, Jaclynn A., Weir, Vanessa R., Hernandez, Nicole S., Stein, Lauren M., Schmidt, Heath D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Springer International Publishing 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969180/
https://ncbi.nlm.nih.gov/pubmed/31581176
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-019-0531-4
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