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Dopamine D(3)R antagonist VK4-116 attenuates oxycodone self-administration and reinstatement without compromising its antinociceptive effects
Prescription opioids such as oxycodone are highly effective analgesics for clinical pain management, but their misuse and abuse have led to the current opioid epidemic in the United States. In order to ameliorate this public health crisis, the development of effective pharmacotherapies for the preve...
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| Publicado en: | Neuropsychopharmacology |
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| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Springer International Publishing
2018
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6785005/ https://ncbi.nlm.nih.gov/pubmed/30555159 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0284-5 |
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