Dopamine D(3)R antagonist VK4-116 attenuates oxycodone self-administration and reinstatement without compromising its antinociceptive effects

Prescription opioids such as oxycodone are highly effective analgesics for clinical pain management, but their misuse and abuse have led to the current opioid epidemic in the United States. In order to ameliorate this public health crisis, the development of effective pharmacotherapies for the preve...

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Bibliografische gegevens
Gepubliceerd in:Neuropsychopharmacology
Hoofdauteurs: You, Zhi-Bing, Bi, Guo-Hua, Galaj, Ewa, Kumar, Vivek, Cao, Jianjing, Gadiano, Alexandra, Rais, Rana, Slusher, Barbara S., Gardner, Eliot L., Xi, Zheng-Xiong, Newman, Amy Hauck
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Springer International Publishing 2018
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6785005/
https://ncbi.nlm.nih.gov/pubmed/30555159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-018-0284-5
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