Newly Developed Dopamine D(3) Receptor Antagonists, R-VK4-40 and R-VK4-116, Do Not Potentiate Cardiovascular Effects of Cocaine or Oxycodone in Rats

Opioid and cocaine abuse are major public health burdens. Existing medications for opioid use disorder are limited by abuse liability and side effects, whereas no treatments are currently approved in the United States for cocaine use disorder. Dopamine D(3) receptor (D(3)R) antagonists have shown pr...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Jordan, Chloe J., Humburg, Bree A., Thorndike, Eric B., Shaik, Anver Basha, Xi, Zheng-Xiong, Baumann, Michael H., Newman, Amy Hauck, Schindler, Charles W.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2019
Assuntos:
Behavioral Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6863462/
https://ncbi.nlm.nih.gov/pubmed/31562201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.119.259390
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