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Ethanol Reversal of Tolerance to the Antinociceptive Effects of Oxycodone and Hydrocodone

This study compared the development of tolerance to two orally bioavailable prescription opioids, oxycodone and hydrocodone, to that of morphine, and the reversal of this tolerance by ethanol. Oxycodone (s.c.) was significantly more potent in the mouse tail-withdrawal assay than either morphine or h...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Jacob, Joanna C., Poklis, Justin L., Akbarali, Hamid I., Henderson, Graeme, Dewey, William L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454589/
https://ncbi.nlm.nih.gov/pubmed/28442580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.241083
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