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Ethanol Reversal of Tolerance to the Antinociceptive Effects of Oxycodone and Hydrocodone

This study compared the development of tolerance to two orally bioavailable prescription opioids, oxycodone and hydrocodone, to that of morphine, and the reversal of this tolerance by ethanol. Oxycodone (s.c.) was significantly more potent in the mouse tail-withdrawal assay than either morphine or h...

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Détails bibliographiques
Publié dans:J Pharmacol Exp Ther
Auteurs principaux: Jacob, Joanna C., Poklis, Justin L., Akbarali, Hamid I., Henderson, Graeme, Dewey, William L.
Format: Artigo
Langue:Inglês
Publié: The American Society for Pharmacology and Experimental Therapeutics 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454589/
https://ncbi.nlm.nih.gov/pubmed/28442580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.241083
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