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Ethanol Reversal of Tolerance to the Antinociceptive Effects of Oxycodone and Hydrocodone

This study compared the development of tolerance to two orally bioavailable prescription opioids, oxycodone and hydrocodone, to that of morphine, and the reversal of this tolerance by ethanol. Oxycodone (s.c.) was significantly more potent in the mouse tail-withdrawal assay than either morphine or h...

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Опубликовано в: :J Pharmacol Exp Ther
Главные авторы: Jacob, Joanna C., Poklis, Justin L., Akbarali, Hamid I., Henderson, Graeme, Dewey, William L.
Формат: Artigo
Язык:Inglês
Опубликовано: The American Society for Pharmacology and Experimental Therapeutics 2017
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC5454589/
https://ncbi.nlm.nih.gov/pubmed/28442580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.241083
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