The mitochondrial negative regulator MCJ modulates the interplay between microbiota and the host during ulcerative colitis

Recent evidences indicate that mitochondrial genes and function are decreased in active ulcerative colitis (UC) patients, in particular, the activity of Complex I of the electron transport chain is heavily compromised. MCJ is a mitochondrial inner membrane protein identified as a natural inhibitor o...

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Publicado en:Sci Rep
Main Authors: Pascual-Itoiz, Miguel Angel, Peña-Cearra, Ainize, Martín-Ruiz, Itziar, Lavín, José Luis, Simó, Carolina, Rodríguez, Héctor, Atondo, Estibaliz, Flores, Juana María, Carreras-González, Ana, Tomás-Cortázar, Julen, Barriales, Diego, Palacios, Ainhoa, García-Cañas, Virginia, Pellón, Aize, Fullaondo, Asier, Aransay, Ana Mª, Prados-Rosales, Rafael, Martín, Rebeca, Anguita, Juan, Abecia, Leticia
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2020
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969106/
https://ncbi.nlm.nih.gov/pubmed/31953445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57348-0
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