Ikaros mediates the DNA methylation-independent silencing of MCJ/DNAJC15 gene expression in macrophages

MCJ (DNAJC15) is a mitochondrial protein that regulates the mitochondrial metabolic status of macrophages and their response to inflammatory stimuli. CpG island methylation in cancer cells constitutes the only mechanism identified for the regulation of MCJ gene expression. However, whether DNA methy...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Navasa, Nicolás, Martin-Ruiz, Itziar, Atondo, Estíbaliz, Sutherland, James D., Angel Pascual-Itoiz, Miguel, Carreras-González, Ana, Izadi, Hooman, Tomás-Cortázar, Julen, Ayaz, Furkan, Martin-Martin, Natalia, Torres, Iviana M, Barrio, Rosa, Carracedo, Arkaitz, Olivera, Elias R., Rincón, Mercedes, Anguita, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4588509/
https://ncbi.nlm.nih.gov/pubmed/26419808
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14692
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