The mitochondrial negative regulator MCJ modulates the interplay between microbiota and the host during ulcerative colitis

Recent evidences indicate that mitochondrial genes and function are decreased in active ulcerative colitis (UC) patients, in particular, the activity of Complex I of the electron transport chain is heavily compromised. MCJ is a mitochondrial inner membrane protein identified as a natural inhibitor o...

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Izdano u:Sci Rep
Glavni autori: Pascual-Itoiz, Miguel Angel, Peña-Cearra, Ainize, Martín-Ruiz, Itziar, Lavín, José Luis, Simó, Carolina, Rodríguez, Héctor, Atondo, Estibaliz, Flores, Juana María, Carreras-González, Ana, Tomás-Cortázar, Julen, Barriales, Diego, Palacios, Ainhoa, García-Cañas, Virginia, Pellón, Aize, Fullaondo, Asier, Aransay, Ana Mª, Prados-Rosales, Rafael, Martín, Rebeca, Anguita, Juan, Abecia, Leticia
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2020
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969106/
https://ncbi.nlm.nih.gov/pubmed/31953445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-57348-0
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