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A robust and efficient method for Mendelian randomization with hundreds of genetic variants
Mendelian randomization (MR) is an epidemiological technique that uses genetic variants to distinguish correlation from causation in observational data. The reliability of a MR investigation depends on the validity of the genetic variants as instrumental variables (IVs). We develop the contamination...
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| Gepubliceerd in: | Nat Commun |
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| Hoofdauteurs: | , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
Nature Publishing Group UK
2020
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6969055/ https://ncbi.nlm.nih.gov/pubmed/31953392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-14156-4 |
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