Caricamento...

Synthesis and biological evaluation of novel (E)-N'-benzylidene hydrazides as novel c-Met inhibitors through fragment based virtual screening

C-Met plays a crucial role in the development and progression of neoplastic disease. Type II c-Met inhibitors recognise the inactive DFG-out conformation of the kinase, result in better anti-tumour effects due to synergistic effect against the other kinases. According to our previous works, an (E)-N...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:J Enzyme Inhib Med Chem
Autori principali: Liang, Jing-wei, Li, Shi-long, Wang, Shan, Li, Wan-qiu, Meng, Fan-hao
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2020
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6968643/
https://ncbi.nlm.nih.gov/pubmed/31902266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1702655
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !