Biological exploration of a novel 1,2,4-triazole-indole hybrid molecule as antifungal agent

(2-(2,4-Dichlorophenyl)-3-(1H-indol-1-yl)-1-(1,2,4-1H-triazol-1-yl)propan-2-ol (8 g), a new 1,2,4-triazole-indole hybrid molecule, showed a broad-spectrum activity against Candida, particularly against low fluconazole-susceptible species. Its activity was higher than fluconazole and similar to voric...

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Detalhes bibliográficos
Publicado no:J Enzyme Inhib Med Chem
Main Authors: Pagniez, Fabrice, Lebouvier, Nicolas, Na, Young Min, Ourliac-Garnier, Isabelle, Picot, Carine, Le Borgne, Marc, Le Pape, Patrice
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2020
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6968525/
https://ncbi.nlm.nih.gov/pubmed/31899979
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2019.1705292
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