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Discovery of a Novel Broad-Spectrum Antifungal Agent Derived from Albaconazole
[Image: see text] Synthesis of a strict structural analogue of albaconazole in which the quinazolinone ring is fused by a thiazole moiety led to the discovery of a new triazole with broad-spectrum antifungal activity. Compound I exhibited high in vitro activity against pathogenic Candida species and...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American
Chemical Society
2013
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4027234/ https://ncbi.nlm.nih.gov/pubmed/24900660 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml300429p |
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