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USP37 Promotes Lung Cancer Cell Migration by Stabilizing Snail Protein via Deubiquitination
Snail is a prominent epithelial–mesenchymal transition (EMT) transcription factor and promotes metastasis. However, Snail protein is unstable and is quickly degraded through ubiquitination-mediated proteasome pathway. Deubiquitinases prevent Snail degradation by regulating the ubiquitination-mediate...
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| Foilsithe in: | Front Genet |
|---|---|
| Main Authors: | , , , , , , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
Frontiers Media S.A.
2020
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6967296/ https://ncbi.nlm.nih.gov/pubmed/31998374 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fgene.2019.01324 |
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