Quality by Design Approach for Development and Characterisation of 
Solid Lipid Nanoparticles of Quetiapine Fumarate

BACKGROUND: Quetiapine fumarate, a 2(nd) generation anti-psychotic drug has oral bioavailability of 9% because of hepatic first pass metabolism. Reports suggest that co-administration of drugs with lipids affects their absorption pathways, enhances lymphatic transport thus bypassing hepatic first-pa...

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Bibliographic Details
Published in:Curr Comput Aided Drug Des
Main Authors: Agarwal, Shweta, Murthy, Rayasa S. Ramachandra, Harikumar, Sasidharan Leelakumari, Garg, Rajeev
Format: Artigo
Language:Inglês
Published: Bentham Science Publishers 2020
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6967136/
https://ncbi.nlm.nih.gov/pubmed/31429691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1573409915666190722122827
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