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Quality by Design Approach for Development and Characterisation of Solid Lipid Nanoparticles of Quetiapine Fumarate
BACKGROUND: Quetiapine fumarate, a 2(nd) generation anti-psychotic drug has oral bioavailability of 9% because of hepatic first pass metabolism. Reports suggest that co-administration of drugs with lipids affects their absorption pathways, enhances lymphatic transport thus bypassing hepatic first-pa...
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| Publicado no: | Curr Comput Aided Drug Des |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Bentham Science Publishers
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6967136/ https://ncbi.nlm.nih.gov/pubmed/31429691 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1573409915666190722122827 |
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