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Investigations of the effect of the lipid matrix on drug entrapment, in vitro release, and physical stability of olanzapine-loaded solid lipid nanoparticles

The purpose of this research was to study the effect of the lipid matrix on the entrapment of olanzapine (OL). OL-loaded solid lipid nanoparticles (SLNs) were prepared using lipids like glyceryl monostearate (GMS), Precirol ATO 5 (PRE), glyceryl tristearate (GTS), and Witepsol E85 (WE 85)—and poloxa...

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Autors principals: Vivek, K., Reddy, Harivardhan, Murthy, Ramachandra S. R.
Format: Artigo
Idioma:Inglês
Publicat: Springer-Verlag 2007
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2750669/
https://ncbi.nlm.nih.gov/pubmed/17408216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/pt0804083
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