Anti-Tumor Effect of Inhibition of DNA Damage Response Proteins, ATM and ATR, in Endometrial Cancer Cells

While the incidence of endometrial cancer continues to rise, the therapeutic options remain limited for advanced or recurrent cases, and most cases are resistant to therapy. The anti-tumor effect of many chemotherapeutic drugs and radiotherapy depends on the induction of DNA damage in cancer cells;...

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Veröffentlicht in:Cancers (Basel)
Hauptverfasser: Takeuchi, Makoto, Tanikawa, Michihiro, Nagasaka, Kazunori, Oda, Katsutoshi, Kawata, Yoshiko, Oki, Shinya, Agapiti, Chuwa, Sone, Kenbun, Miyagawa, Yuko, Hiraike, Haruko, Wada-Hiraike, Osamu, Kuramoto, Hiroyuki, Ayabe, Takuya, Osuga, Yutaka, Fujii, Tomoyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966633/
https://ncbi.nlm.nih.gov/pubmed/31805725
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11121913
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