Inhibition of Histone Demethylases LSD1 and UTX Regulates ERα Signaling in Breast Cancer

In breast cancer, Lysine-specific demethylase-1 (LSD1) and other lysine demethylases (KDMs), such as Lysine-specific demethylase 6A also known as Ubiquitously transcribed tetratricopeptide repeat, X chromosome (UTX), are co-expressed and co-localize with estrogen receptors (ERs), suggesting the pote...

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Vydáno v:Cancers (Basel)
Hlavní autoři: Benedetti, Rosaria, Dell’Aversana, Carmela, De Marchi, Tommaso, Rotili, Dante, Liu, Ning Qing, Novakovic, Boris, Boccella, Serena, Di Maro, Salvatore, Cosconati, Sandro, Baldi, Alfonso, Niméus, Emma, Schultz, Johan, Höglund, Urban, Maione, Sabatino, Papulino, Chiara, Chianese, Ugo, Iovino, Francesco, Federico, Antonio, Mai, Antonello, Stunnenberg, Hendrik G., Nebbioso, Angela, Altucci, Lucia
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966629/
https://ncbi.nlm.nih.gov/pubmed/31888209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11122027
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