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Somatic Mutation of PIK3CA (H1047R) Is a Common Driver Mutation Hotspot in Canine Mammary Tumors as Well as Human Breast Cancers

Breast cancer is one of the most frequently diagnosed cancers in both women and female dogs. Genome-wide association studies in human breast cancer (HBC) have identified hundreds of genetic variations and somatic driver mutations. However, only a handful of variants have been studied for rare HBC an...

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Detalhes bibliográficos
Publicado no:Cancers (Basel)
Main Authors: Lee, Kang-Hoon, Hwang, Hyeon-Ji, Noh, Hyun Ji, Shin, Tae-Jin, Cho, Je-Yoel
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6966585/
https://ncbi.nlm.nih.gov/pubmed/31842489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers11122006
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