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“An End to a Means”: How DNA-End Structure Shapes the Double-Strand Break Repair Process
Endogenously-arising DNA double-strand breaks (DSBs) rarely harbor canonical 5′-phosphate, 3′-hydroxyl moieties at the ends, which are, regardless of the pathway used, ultimately required for their repair. Cells are therefore endowed with a wide variety of enzymes that can deal with these chemical a...
Shranjeno v:
| izdano v: | Front Mol Biosci |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Frontiers Media S.A.
2020
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6965357/ https://ncbi.nlm.nih.gov/pubmed/31998749 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2019.00153 |
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