Multiple Dynamical Mechanisms of Phase-2 Early Afterdepolarizations in a Human Ventricular Myocyte Model: Involvement of Spontaneous SR Ca(2+) Release

Early afterdepolarization (EAD) is known to cause lethal ventricular arrhythmias in long QT syndrome (LQTS). In this study, dynamical mechanisms of EAD formation in human ventricular myocytes (HVMs) were investigated using the mathematical model developed by ten Tusscher and Panfilov (Am J Physiol H...

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Detaylı Bibliyografya
Yayımlandı:Front Physiol
Asıl Yazarlar: Kurata, Yasutaka, Tsumoto, Kunichika, Hayashi, Kenshi, Hisatome, Ichiro, Kuda, Yuhichi, Tanida, Mamoru
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Frontiers Media S.A. 2020
Konular:
Physiology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965073/
https://ncbi.nlm.nih.gov/pubmed/31998140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01545
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