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Dynamical Mechanisms of Pacemaker Generation in I(K1)-Downregulated Human Ventricular Myocytes: Insights from Bifurcation Analyses of a Mathematical Model

Dynamical mechanisms of the biological pacemaker (BP) generation in human ventricular myocytes were investigated by bifurcation analyses of a mathematical model. Equilibrium points (EPs), periodic orbits, stability of EPs, and bifurcation points were determined as functions of bifurcation parameters...

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Detalhes bibliográficos
Main Authors: Kurata, Yasutaka, Hisatome, Ichiro, Matsuda, Hiroyuki, Shibamoto, Toshishige
Formato: Artigo
Idioma:Inglês
Publicado em: Biophysical Society 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1366784/
https://ncbi.nlm.nih.gov/pubmed/16040746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.060830
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