PAK Kinases Target Sortilin and Modulate Its Sorting

The multifunctional type 1 receptor sortilin is involved in endocytosis and intracellular transport of ligands. The short intracellular domain of sortilin binds several cytoplasmic adaptor proteins (e.g., the AP-1 complex and GGA1 to -3), most of which target two well-defined motifs: a C-terminal ac...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Pallesen, Lone Tjener, Gustafsen, Camilla, Cramer, Jacob Flyvholm, Petersen, Steen Vang, Thirup, Søren Skou, Madsen, Peder, Petersen, Claus Munck
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6965034/
https://ncbi.nlm.nih.gov/pubmed/31767632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00411-19
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