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Revisiting the structure of the Vps10 domain of human sortilin and its interaction with neurotensin
Sortilin is a multifunctional receptor involved in sorting and apoptosis. We have previously reported a 2.0-Å structure of the Vps10 ectodomain in complex with one of its ligands, the tridecapeptide neurotensin. Here we set out to further characterize the structural properties of sortilin and its in...
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| Publicado no: | Protein Sci |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Blackwell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4243999/ https://ncbi.nlm.nih.gov/pubmed/24985322 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2512 |
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