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First eight residues of apolipoprotein A-I mediate the C-terminus control of helical bundle unfolding and its lipidation

The crystal structure of a C-terminal deletion of apolipoprotein A-I (apoA1) shows a large helical bundle structure in the amino half of the protein, from residues 8 to 115. Using site directed mutagenesis, guanidine or thermal denaturation, cell free liposome clearance, and cellular ABCA1-mediated...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Brubaker, Gregory, Lorkowski, Shuhui W., Gulshan, Kailash, Hazen, Stanley L., Gogonea, Valentin, Smith, Jonathan D.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2020
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964839/
https://ncbi.nlm.nih.gov/pubmed/31945064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221915
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