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Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer

BACKGROUND: Increased numbers of myeloid-derived suppressor cells (MDSCs) are positively correlated with poor prognosis and reduced survivals of cancer patients. They play central roles in tumor immune evasion and tumor metastasis. However, limited data are available on phenotypic/transcriptomic cha...

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Publicat a:Clin Epigenetics
Autors principals: Sasidharan Nair, Varun, Saleh, Reem, Toor, Salman M., Taha, Rowaida Z., Ahmed, Ayman A., Kurer, Mohamed A., Murshed, Khaled, Alajez, Nehad M., Abu Nada, Mohamed, Elkord, Eyad
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964037/
https://ncbi.nlm.nih.gov/pubmed/31941522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-0808-9
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