Transcriptomic profiling disclosed the role of DNA methylation and histone modifications in tumor-infiltrating myeloid-derived suppressor cell subsets in colorectal cancer

BACKGROUND: Increased numbers of myeloid-derived suppressor cells (MDSCs) are positively correlated with poor prognosis and reduced survivals of cancer patients. They play central roles in tumor immune evasion and tumor metastasis. However, limited data are available on phenotypic/transcriptomic cha...

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Vydáno v:Clin Epigenetics
Hlavní autoři: Sasidharan Nair, Varun, Saleh, Reem, Toor, Salman M., Taha, Rowaida Z., Ahmed, Ayman A., Kurer, Mohamed A., Murshed, Khaled, Alajez, Nehad M., Abu Nada, Mohamed, Elkord, Eyad
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6964037/
https://ncbi.nlm.nih.gov/pubmed/31941522
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13148-020-0808-9
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