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Opening the OPK Assay Gatekeeper: Harnessing Multi-Modal Protection by Pneumococcal Vaccines

Pneumococcal vaccine development is driven by the achievement of high activity in a single gatekeeper assay: the bacterial opsonophagocytic killing (OPK) assay. New evidence challenges the dogma that anti-capsular antibodies have only a single function that predicts success. The emerging concept of...

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Detalhes bibliográficos
Publicado no:Pathogens
Main Authors: Riegler, Ashleigh N., Mann, Beth, Orihuela, Carlos J., Tuomanen, Elaine
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6963391/
https://ncbi.nlm.nih.gov/pubmed/31652741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/pathogens8040203
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