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Pneumococcal neuraminidase activates TGF-β signalling
Neuraminidase A (NanA) is an important virulence factor that is anchored to the pneumococcal cell wall and cleaves sialic acid on host substrates. We noted that a secreted allele of NanA was over-represented in invasive pneumococcal isolates and promoted the development of meningitis when swapped in...
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| Publicado no: | Microbiology (Reading) |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Microbiology Society
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5817201/ https://ncbi.nlm.nih.gov/pubmed/28749326 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.000511 |
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