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Adiponectin inhibits NLRP3 inflammasome by modulating the AMPK-ROS pathway

Chronic inflammation is a key contributor to obesity-related insulin resistance and type 2 diabetes (T2D). NLRP3 inflammasome activation plays an important role in impairing insulin signaling and insulin sensitivity. Adiponectin is an adipocyte-derived cytokine that has been shown to promote insulin...

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Bibliographische Detailangaben
Veröffentlicht in:Int J Clin Exp Pathol
Hauptverfasser: Wang, Fang, Liu, Yuxing, Yang, Wenjun, Yuan, Jingjing, Mo, Zhaohui
Format: Artigo
Sprache:Inglês
Veröffentlicht: e-Century Publishing Corporation 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962845/
https://ncbi.nlm.nih.gov/pubmed/31949710
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