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Adiponectin inhibits NLRP3 inflammasome by modulating the AMPK-ROS pathway
Chronic inflammation is a key contributor to obesity-related insulin resistance and type 2 diabetes (T2D). NLRP3 inflammasome activation plays an important role in impairing insulin signaling and insulin sensitivity. Adiponectin is an adipocyte-derived cytokine that has been shown to promote insulin...
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| Pubblicato in: | Int J Clin Exp Pathol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
e-Century Publishing Corporation
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6962845/ https://ncbi.nlm.nih.gov/pubmed/31949710 |
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