Recurrent Genetic Abnormalities in Human Pluripotent Stem Cells: Definition and Routine Detection in Culture Supernatant by Targeted Droplet Digital PCR

Genomic integrity of human pluripotent stem cells (hPSCs) is essential for research and clinical applications. However, genetic abnormalities can accumulate during hPSC generation and routine culture and following gene editing. Their occurrence should be regularly monitored, but the current assays t...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Stem Cell Reports
Auteurs principaux: Assou, Said, Girault, Nicolas, Plinet, Mathilde, Bouckenheimer, Julien, Sansac, Caroline, Combe, Marion, Mianné, Joffrey, Bourguignon, Chloé, Fieldes, Mathieu, Ahmed, Engi, Commes, Thérèse, Boureux, Anthony, Lemaître, Jean-Marc, De Vos, John
Format: Artigo
Langue:Inglês
Publié: Elsevier 2020
Sujets:
Report
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6962701/
https://ncbi.nlm.nih.gov/pubmed/31902703
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stemcr.2019.12.004
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires